Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep1001 | Hot topics (including COVID-19) | ECE2020

Obstructive sleep apnea in primary aldosteronism is associated with cortisol cosecretion

Heinrich Daniel , Adolf Christian , Handgriff Laura , Schneider Holger , Nirschl Nina , Obster Elisabeth , Sturm Lisa , Wang Xiao , Bidlingmaier Martin , Wildgruber Moritz , Ladurner Roland , Beuschlein Felix , Reincke Martin

Background: Primary aldosteronism (PA) is a secondary form of arterial hypertension that – in case of unilateral disease – can be cured by surgery. Multiple studies have shown that PA patients are at higher risk to suffer from cardiovascular events and to develop metabolic diseases. Two thirds of patients with PA suffer from obstructive sleep apnea (OSA). A bi-directional, pathophysiological interplay between OSA and PA has been proposed, with focus on overnight ro...

ea0081oc13.2 | Oral Communications 13: Adrenal and Cardiovascular Endocrinology 2 | ECE2022

Early post-operative ACTH-stimulated aldosterone predicts long-term biochemical outcome in primary aldosteronism

Bruedgam Denise , Adolf Christian , Schneider Holger , Wegmann Verena , Schwarzlmueller Paul , Mueller Lisa , Holler Finn , Lechner Benjamin , Handgriff Laura , Ladurner Roland , Deniz Sinan , Williams Tracy Ann , Beuschlein Felix , Reincke Martin , Heinrich Daniel

Introduction: Primary aldosteronism (PA) is the most common surgically curable cause for endocrine hypertension. Patients with unilateral aldosterone-producing adenoma undergo adrenalectomy (ADX). Clinical and biochemical outcome is assessed 6-12 months after ADX according to PASO consensus. To reduce unnecessary follow-up visits and change in medication for diagnostic purposes for potentially cured patients after ADX, a prediction tool is needed. Previous research had shown g...